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Written by clinicians and scientists at the National Institutes of Health and other leading institutions, the Bethesda Handbook of Clinical Hematology, Second Edition is a concise, complete hematology handbook designed for quick bedside consultation. The book covers all hematologic disorders and provides residents, fellows, and practitioners with need-to-know information on pathophysiology, natural history, risk factors, diagnosis, treatment, and follow-up. The succinct yet detailed presentation is ideal for board review as well as clinical reference. This thoroughly updated edition includes new information on supportive care and new therapies, including immunomodulatory drugs, growth factors, and epigenetic-acting agents and their role in selected disorders.